It can be a long, dull slog, especially if you're lousy chess player like me: the endgame.
The SARS-CoV-2 endgame is looking that way, too: a bumpy road to endemicity, short or long. As one of the interviewees puts it in this AP article, "We're not going to get to...2019 again." I had hoped we could kill this bug dead, or at least knock it down as hard as we did with polio. It's not going to happen. COVID-19's going to get settled in, right next to the flu -- and shots for it will become as commonplace as yearly flu shots.
Elsewhere, an illustration of the dangers of reading only the headlines. That "study proving a single COVID-19 infection makes you immune for life?" The guy in charge of the study says nope, that's not what we found. The good news is, it does help some -- about like getting a single vaccine shot. Of course, the vaccine is enormously less risky.
How risky is too risky? That "99% survivable" rate that gets bandied about for a COVID-19 infection? An amusement-park roller-coaster can average 100 riders an hour. If one rider died on it every hour, it's 99% survivable. Who would line up for that?*
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* I have done the math for deaths connected to vaccination. The very worst-case VAERS numbers give a 1 in 55,555 chance; using the confirmed death rate works out, very roughly, to less than one in 30 million. Either is considerably better odds than one in a hundred.
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